WIC1, CAS 943083-58-7

Formulation: A solid

Formal Name: N-[4-(4-ethyl-1-piperazinyl)phenyl]-2-oxo-2H-1-benzopyran-3-carboxamide

Purity: ≥98%

Formula Markup: C22H23N3O3

Formula Weight: 377,4

Shelf life (days): 1460

CAS Number: 943083-58-7

Notes: WIC1 is an inhibitor of Wnt signaling.{51513} It inhibits Wnt signaling induced by the glycogen synthase kinase 3β (GSK3β) inhibitor CHIR99021 (Item No. 13122) in a reporter assay using BEAS-2B cells when used at a concentration of 100 nM. WIC1 (1 µM) induces differentiation of, and decreases CHIR99021-induced hyperproliferation of, and nuclear phosphorylation of β-catenin in, isolated mouse airway basal stem cells (ABSCs).

• SKU: CAY39574-25
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 39574-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK