WP-1130, CAS 856243-80-6

DUB inhibitor

Product Type: Inhibitor

CAS No.: 856243-80-6

MolecularFormula: C19H18BrN3O

Molecular Weight: 384,3

Source: Synthetic

Purity: >98%

Solubility: Soluble in 45 mg/ml DMSO, 25 mg/ml Ethanol

Appearance: Pale Yellow Solid

PubChem CID: 11222830

Scientific Background: A novel DUB inhibitor directly inhibiting USP9x, USP5, USP14 and UCH37 inducing rapid accumulation of polyubiquitinated proteins. Blocks Jak2 signaling via Jak2 ubiquitination.

References: 1. KapuriaV., et al. (2010) Cancer Res. 70: 9265.2. Kapuria V., et al. (2011) Cell Signal. 23: 2076.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-337-5MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-337-5MG
• Package Unit: 5 mg
• Quantity Unit: STK