Xanthohumol, CAS 6754-58-1

Autophagy inhibitor

Product Type: Inhibitor

CAS No.: 6754-58-1

MolecularFormula: C21H22O5

Molecular Weight: 354,4

Source: Synthetic

Purity: ≥98% (TLC); NMR (Conforms)

Solubility: May be dissolved in DMSO (35 mg/ml) or Ethanol (35 mg/ml)

Appearance: Yellow solid

PubChem CID: 639665

Scientific Background: Xanthohumol is a valosin-containing protein (VCP) inhibitor which binds to the N-domain of VCP, suppressing function and impairing autophagosome maturation (1). It also inhibits growth of a wide variety of human cancer cell lines by inhibiting proliferation and inducing apoptosis (2).

References: 1. Sasazawa Y., et al. (2012) ACS Chem Biol. 7(5): 892-900.2. Vene R., et al. (2012) Mol. Med. 18: 1292.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• SKU: STRSIH-370-10MG
• Manufacturer: Stressmarq Biosciences
• Manufacturer SKU: SIH-370-10MG
• Package Unit: 10 mg
• Quantity Unit: STK