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Applications: This enzyme is active towards Ubiquitin-AMC and Ubiquitin-Rhodamine.
Background: Yod1 is the mammalian homolog of the S. cerevisiae protein Otu1.Otu1 has been demonstrated to bind Cdc48p and degrade polyubiquitin chains.
Description: Human Yod1 recombinant protein, with His-tag, expressed in E. coli.
Format: Aqueous buffer solution
Purity: ≥90% by SDS-PAGE
Storage Stability: Store at or below -80°C. Stable as supplied for up to 1 year when stored dessicated at -80°C.
Tags: His-tag
Uniprot: Q5VVQ6
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: Rumph, S., and Jentsch, S. Functional division of substrate processing cofactors of the ubiquitin-selective Cdc48 chaperone. Mol Cell. 2006. 21(2): 261-9.