Z-Ala-Ala-Asn-AMC, CAS 149697-16-5

Product Description: Z-Ala-Ala-Asn-AMC (Cbz-Ala-Ala-Asn-AMC) is the legumain substrate. Overexpressed legumain in 293 HEK-Leg cells potently cleaved CBZ-Ala-Ala-Asn-AMC[1].

Applications: Cancer-programmed cell death

Formula: C28H31N5O8

References: [1]Stern L, Perry R, Ofek P, Many A, Shabat D, Satchi-Fainaro R. A novel antitumor prodrug platform designed to be cleaved by the endoprotease legumain. Bioconjug Chem. 2009;20(3):500-510./[2]James C. Powers, et al. Propenoyl hydrazides. US7482379B2./[3]Poreba M, et al. Counter Selection Substrate Library Strategy for Developing Specific Protease Substrates and Probes. Cell Chem Biol. 2016;23(8):1023-1035.

CAS Number: 149697-16-5

Molecular Weight: 565.57

Compound Purity: 99.47

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: Fluorescent Dye

• SKU: MEXHY-136626-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-136626-1
• Package Unit: 1 mg
• Quantity Unit: STK