Zapnometinib, CAS 303175-44-2

Formulation: A solid

Formal Name: 2-[(2-chloro-4-iodophenyl)amino]-3,4-difluoro-benzoic acid

Purity: ≥95%

Formula Markup: C13H7ClF2INO2

Formula Weight: 409,6

Shelf life (days): 1460

CAS Number: 303175-44-2

Notes: Zapnometinib is a MEK inhibitor (IC50 = 5.73 nM) and an active metabolite of CI-1040 (Item No. 11580).{51346,51347} It reduces viral titers in A549 and MDCK cells infected with influenza A (EC50s = 6.356 and 4.498 µM, respectively).{51347} Zapnometinib (50 mg/kg per day) increases survival in H1N1pdm09 influenza A-infected mice.

• SKU: CAY38517-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 38517-5
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Reinstoffe