Abbreviation: ZDHHC17
Target Synonym: ZDHHC17;HIP14;HIP3;HSPC294;HYPH
Conjugation: Unconjugated
UNIProt ID: Q8IUH5
Background: Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and is involved in a variety of cellular processes. Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA (By similarity. Palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HTT. Also palmitoylates neuronal protein GPM6A as well as SPRED1 and SPRED3. Could also play a role in axonogenesis through the regulation of NTRK1 and the downstream ERK1/ERK2 signaling cascade (By similarity. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. May play a role in Mg(2+ transport. Could also palmitoylate DNAJC5 and regulate its localization to the Golgi membrane (By similarity.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human ZDHHC17
Dilution: WB 1:500-1:2000
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