Scientific Background: Potentiates TRAIL-induced apoptosis via upregulation of death receptor DR4 and DR5 expression. Has no cytotoxic effect on normal cells. Cell permeable. Natural sesquiterpene ketone isolated from Zingiber sp.
References: 1. Leu J.L., et al. (2009) Mol Cell. 36:15.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.