Zidesamtinib, CAS 2739829-00-4

Description: Zidesamtinib (NVL-520) is an orally active, selective, potent, and blood-brain-barrier-crossing inhibitor of ROS1 fusion and resistance mutations, inhibits ROS1 and ROS1 G2032R, and can be used in the study of non-small-cell lung cancer and solid tumors.

CAS Number: 2739829-00-4

Formula: C22H22FN7O

Molecular Weight: 419,455

References: Drilon A, et al. NVL-520 is a selective, TRK-sparing, and brain-penetrant inhibitor of ROS1 fusions and secondary resistance mutations. Cancer Discov. 2022 Dec 13;CD-22-0968.

• SKU: TGMT72953-1mL
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T72953-1mL
• Package Unit: 1 mL
• Quantity Unit: STK